Adolescents were asked to maintain abstinence from alcohol and other substances from the time they completed their CDDR; the initial appointment was scheduled to coincide with 4-10 days of abstinence. This ensured that any cognitive impairment observed in the heavy drinkers could not be indicative of acute alcohol withdrawal and detoxification. Adolescents completed a TLFB at […]
Author: mobilegrow
Hemodialysis is a viable option for treatment of VPA induced hyperammonemia
Elimination occurs via first-order kinetics with a half-life of 5-20 hours; however, this can be prolonged up to 30 hours with toxicity.At toxic levels, VPA can cause central nervous system depression, respiratory depression, acute kidney injury, anion-gap metabolic acidosis, and electrolyte abnormalities . VPA is also associated with hepatotoxicity, pancreatitis, hyperammonemic encephalopathy, cerebral edema, and blood […]
Hippocampal and prefrontal white matter volumes appear smaller in heavy alcohol using adolescents
Approximately 8% of those ages 12–17 meet criteria for substance abuse or dependence in the past year, but this peaks between ages 18–25, when 21% meet diagnostic criteria for a substance use disorder . Those with early substance use onset are more likely to continue use into adulthood; individuals who first used alcohol at age […]
Stimuli presentation and data collection used E-Prime software
Our results indicate that screening, along with brief interventions and referrals to treatment, may be particularly important for identifying and providing early intervention for women of reproductive age prior to conception who may be at greater risk for prenatal alcohol and nicotine use. It is important that these conversations are supportive and non-punitive, focused on […]
Analyzing the DNA of natural fiber rope components can be valuable for several reasons
The results of the restriction digest of the grass stain-covered sisal rope indicated that if this were an unknown piece of rope, it would be difficult to determine its identity. Through analysis of restriction bands, three out of five types of rope could be eliminated, resulting in the unknown being either sisal rope with contamination […]
The same age grouping was used for regular alcohol use for comparative purposes
The amplitudes were calculated using the S-transform applied to the recorded data for the delta frequency band extending from 300 to 700 ms post-stimulus. Jones et al. provides a complete description of the experiment and the calculation of the values. The values were log transformed and non-parametric age regression was performed on the variables and the standardized residuals […]
Geographic disparities in the severity of punishment for drug offenses are also stark
Research conducted in 2010 in California found the proportion of arrests for possession of a controlled substance that were charged as felonies varied across California counties from 25 to 100 percent . Even after controlling for case characteristics and criminal history, county of residence was a strong predictor of felony filings following arrest . Many […]
A significant indirect effect is indicated when the CI does not include the value zero
The retrospective nature of this study limits the conclusions that can be determined as the methodology was not able to ascertain any measure of acute versus chronic marijuana use. Urine toxicology screens, such as those used in the ED, detectable levels of THC can be present for up to 4.6 days after the last noted […]
Correlates that are identified as significant will become covariates in the adjusted prevalence analysis
These basic summary statistics will be calculated for continuous variables and binary categorical variables . Continuous variables will be plotted to assess for normality; tests to assess for normality will include kurtosis and skewness. If data is normally distributed, then parametric statistics will be utilized. If data is not normally distributed, then non-parametric statistics will be […]
There was no association between dose or length of CBD usage and ALT levels
The 839 individuals who completed the study came from 43 states, including Alaska and the District of Columbia. Of these, 548 were female and 291 were male. Age ranged from 18 to 75 with the mean – SD of 45.5 + 13.1 years. There was no statistical difference in age between females and males . The percent […]