Methods exist for extraction of cannabinoids from oral fluid using the Quantisal device. However, the goal of this manuscript is to combine previous methods into a single extraction procedure without a hydrolysis step that would allow for the quantification of the following compounds by one method: THC, cannabidiol , cannabinol , cannabigerol , Δ9 -tetrahydrocannabinolic acid […]
Author: mobilegrow
Cannabis dependence status was determined by the SCIDI–N/P for DSM-IV
Mixed evidence for the combined impact of alcohol use and HIV infection on memory functioning may be attributable to different stratifications of alcohol use , presence of co-occurring substance use and mental health conditions, as well as assessment method. For example, standardized laboratory-based neuropsychological testing tends to assess performance at a single time point and […]
The analysis found that 87% of patients substituted cannabis for one or more substances
Our use of provider-assigned diagnoses restricted our sample to ICD-9 codes assigned during health plan visits. This method is vulnerable to diagnostic under-estimation; and thus, the rates of bipolar and schizophrenia may be somewhat higher than we report. Another potential limitation with the methods used to select the sample is that we required a single […]
Cannabis legalization categories were assigned to participants based on their state of residence
The curated GIS database compiled by the ABCD Study LED Environment Working Group includes both vector and raster data of multiple built and natural environmental contextual variables. As shown in Table 1 and outlined in greater detail below, various environmental datasets have been used to map environmental factors to the state-, census-, residential-level for ABCD […]
It is notable that the use of cannabis is associated with a higher prevalence of periodontitis
In our experiments we presented the olfactory and visual stimuliCannabis sativa contains more than 140 terpene-like compounds, called cannabinoids, that share the cannabinoid chemical scaffold. The 2 main members of this chemical family are Δ9 -tetrahydrocannabinol and cannabidiol . Animal and human studies have demonstrated that THC is responsible for the majority of the intoxicating effects of cannabis; […]
Disparities exist in the rates of overdoses due to amphetamines by race/ethnicity and gender
Galve-Roperh et al. found that cannabinoids cause a bi-phasic increase in ceramide levels in C6 glioma cells. The first phase of ceramide accumulation occurred within seconds or minutes after cannabinoid administration, which was likely to be a result of stimulus-dependent hydrolysis of sphingomyelin. Two days after the addition of the drug, a second increase in […]
Scoring was based on the total correct responses for congruent and in congruent trials
The 12-item Electronic Cigarette Attitudes Survey was administered to further examine attitudes toward the use of e-cigarettes versus combustible NTP. The Questionnaire of Smoking Urges and the Hooked on Nicotine Checklist were also given to NTP users to acquire information on NTP addiction severity, with total scores calculated. Neurocognition, NIH Toolbox: Participants completed the National Institutes of […]
2-AG might also be synthesized by the hydrolysis of lysophospholipids or triacylglycerols
Since the discovery of the first cannabinoid receptor 12 years ago1,2, important advances have been made in several areas of cannabinoid pharmacology. Endocannabinoid compounds and their pathways of biosynthesis and inactivation have been identified, and the molecular structures and anatomical distribution of cannabinoid receptors have been investigated in detail. Pharmacological agents that interfere with various […]
Multilevel regression models were used to examine change over time for SSIS
Participants’ responses to the ASSIST during the SBIRT intervention procedure were not used to determine this outcome.Baseline demographic characteristics and SSIS were summarized with descriptive statistics.Major advantages of multilevel regression over traditional repeated measures analysis include the fact that cases are not dropped due to missing observations on the dependent variable at any assessment, numeric […]
This appears likely due to the volatility of the aerosol from the cannabis vaping pen
Side stream smoke, which is emitted directly from the source between puffs and not exhaled by the smoker, has been shown to produce greater emissions than mainstream smoke . Based on observations of the participant, the inhalation time of the puff was about 2 s, and the exhalation time was ~2–4 s, making the total puff […]