The identified increase in variance explained by PTSD emphasizes that PTSD is a significant predictor of later addiction severity among individuals who face early substance use problems. These results are consistent with previous research, which associated early childhood experience of trauma with early substance use onset and transition to poly drug use . Additionally, previous handful […]
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None of the participants had ever been treated with psychotropic medications
The increasing use of more discreet forms of vaping, particularly JUUL , may also have had an impact on social media engagement about vaping behavior, though more research is needed. Also, the associated health risks of vaping were relatively unknown during the study period, though the outbreak of EVALI in 2019 may have generated more […]
The TreeNet analysis revealed a set of predictors for SUD containing those derived by CART
Each of the four types of sub stances, as well as daily use of tobacco and the number of substance use classes endorsed , were explored in secondary analyses. DSM-IV abuse or dependence was based on a positive parent or child report with the Diagnostic Interview Schedule for Children version 2.3/3.0 at the 6- and 8-year follow-up […]
Nicotine patches are usually placed on the skin in the morning and deliver nicotine over 16 to 24 hours
However, a 2015 review of 225 Android apps for quitting smoking found that most provide simplistic tools ; use of tailoring was limited, although positively related to app popularity and user ratings of quality .Notably, one randomized trial found that a simpler, direct texting program outperformed a smoking cessation app . Social media. Social media, such […]
Capsaicin may reduce release of neuropeptides that are active at neurogenic pain onset
Of note, CGRP plasma levels positively correlate with headache intensity and timing , and CGRP intravenous infusion causes migraine-like symptoms in migraine patients . The acute treatment of migraine relies on compounds specifically developed for the disease, such as the triptans . In contrast, prophylactic treatment has relied on drugs originally developed for other disorders, […]
These compounds with little excitatory capacity rapidly sensitize the transduction of nociceptors
These results indicate that clinicians and researchers should give adequate consideration to which AUD criteria might be most salient in identifying older versus younger drinkers with persistent problems who might benefit from interventions and treatment. The need to consider changes in endorsement patterns of specific items in different age groups could also be important for […]
In the twin studies post-onset presence of the condition is part of the outcome analyzed
The proportion of the at-risk sample who become regular users of alcohol increased from 15 to 43 % between the two age ranges. Biological factors are significant in both the onset of regular alcohol use and of alcohol dependence in the youngest age range. The prevalence of regular drinking in the oldest age range has eliminated the effect […]
Individuals with severe mental illness may be prone to develop SUDs
For participants with regular drinking, we asked participants how many drinks they consumed in a typical day using a question modified from NSHAPC.If participants drank 5 or more equivalents in a day, we classified this as binge drinking.We asked participants to report if they had ever received treatment for use of alcohol or illicit substances. […]
Drugs of abuse provide rewarding, pleasurable feelings that contribute to its reinforcement
The depth of this understanding, specifically the molecular consequences of adolescent nicotine use, allows for individualized treatment plans with a greater emphasis on medication interactions, care coordination, community resources, education, and advocacy. These clinical adjustments may contribute to decreases in addiction and drug-related emergencies.Prior to drafting this manuscript, the two authors independently evaluated and summarized […]
Our findings in Fresno County identified both similar and different risk factors for preterm birth
Data used for the study were received by the California Preterm Birth Initiative at the University of California San Francisco by June 2016.Not only did the risk models differ by residence within Fresno County, but the percentage of women with the risk varied greatly for some factors. In urban residences, 12.2% of women with preterm births […]