Our findings suggest that cannabinoids are capable of altering the differentiation and activation of cells involved in human cell-mediated immunity. Functional coupling of cannabinoid receptors to G-protein activity was assessed by measuring forskolin-induced cAMP levels in CHO-CB2 cells and fresh human monocytes. CHO-CB2 cells were cultured overnight at 5×105 cells/well in a 6-well plate. The […]