The relative heights of the two peaks differ in different age groups

As there were multiple observations per individual , a random intercept was used for individuals. Utilization of places for each person was estimated using two different approaches. The first method was by checking whether more than two temporally-consecutive GPS points of a person fall within a polygon designated for the person’s home , farms, or forests on each day. This is equivalent to checking if a person spent at least an hour within the same polygon. For each participant, the number of days spending in each category of place was divided by the total number of days participated during the study period to obtain the proportion of being at the respective places. The second method estimated the utilization of places by a biased random bridge technique. Unlike priormethods for estimation of utilization of places such as location-based kernel density estimations , BRB takes the activity time between successive relocations into account and models space utilization as a time-ordered series of points to improve accuracy and biological relevance while adjusting for missing values. BRB estimates the probability of an individual being in a specific location during the study time period and can be used to estimate home range . To parameterize BRB models for each individual, we considered points collected more than three hours apart to be uncorrelated. However, the two temporally-consecutive points that are deemed uncorrelated by the prior cutoff, may in fact be correlated . Without manually adding points between them, 4×4 flood tray this method will underestimate the usage of homes. An individual is considered stationary when the distance between two consecutive points is less than 10 meters.

The minimum standard deviation in relocation uncertainty is set at 30 meters. For each individual, estimation for the usage of different places was done for the whole study period and for each season as described below. In Central and Southern Myanmar, the monsoon rain starts in mid-May and ends in mid-October. Therefore, we split the data on 15th May 2017 and 15th October 2017, and the period between the two dates was regarded as the “rainy season”. Mid-October to mid-March is the “cool and dry season”, mid-March to mid-May is the “hot and dry season”. Combinations of the two dry seasons had been used simply as the “dry season” in some of the analyses.The violin plot of the maximum daily Euclidian distances traveled in kilometers in log10 scale shows that there is a bimodal distribution for all three age groups. The violin plot is a hybrid of kernel density plot and box-plot with the axes flipped that is particularly used to describe data with multi-modal distribution. In the figure the vertical axis is the distance value in kilometers with the smallest value at the bottom, and the horizontal axis shows the density value. The heights and peaks in the following results refer to the width/broadness of the violins in the horizontal axis. The first peak was between 0.01 to 0.1 kilometers and the second peak was between 1 and 10 kilometers. For under 20s, the first peak is over 20% higher compared to the second peak. The difference between the two peaks in the other two age groups is less than 10%. The Wilcoxon rank-sum tests provided evidence that 20–40 and over-40 age groups have greater maximum daily Euclidian distances away from home compared to under-20 age group on average. Further disaggregation of this data by gender, and age group can be found in the Extended data: Figure S4.

Participants may make trips that would last several days, either because their destination could not be reached within a single day or because they stayed at their destination for several days . Using a buffer radius of 266 meters around their home GPS points as their home locations, we calculated the number of consecutive days they spent away from home. Aside from two participants , all other participants had at least one trip with more than two consecutive days away from home during their participation period. Trips of less than 10 consecutive days are the most frequent among the participants. There are male outliers of over 20-years old who took shorter consecutive day trips over 10 times. Making trips of over 10 consecutive days was relatively uncommon, but 21 participants still made at least one trip of over 20 consecutive days away from home. For each participant, we identified the number of days spent at farms, forests, or at one’s home, and looked for an association between farm visits and forest visits. Here we assumed that having at least two GPS points in the polygon of a particular place constitutes using the respective place for that day, and that a person can be at various types of places in a single day. We found that if a person spent a higher proportion of days at the farms, she or he will likely spend a lower proportion of days at the forests, and vice versa, even though both being at the farms and being in the forests are possible on the same day. Figure 2 shows the distribution of the proportion of the number of days being at the farms, forests or home for different age groups. All participants were found to be at their respective home for the majority of days. Compared to other age groups, the 20–40 age group had a higher proportion of time spent in the forests. The under-20 group had the highest proportion of time spent in the farms on average, followed by the 20–40 age group.

We also combined the geographic information of farms and forests with the place utilization estimated from a biased-random bridge algorithm, and calculated the utilization of each specific place over the study period . An example of the place utilization of a person can be seen in Figure 3. On average, participants in the under-20 age group spent 20.0% and 2.2% of their time in farms and forests, respectively. For the participants from the 20–40 age group the percentages are 7.6% and 7.4%, and for those in the over-40 age group, hydroponic tray the percentages are 7.2% and 3.8%, respectively.Being in the farms and forests at night might impose increased risks of diseases such as malaria because of potential exposure to important mosquito vector species . As seen in Figure 4, we looked at the total number of nights participants spent in the farms or in the forests. Two female participants spent at least a night in the farm compared to 22 male participants . As for spending at least a night in the forest, there were 21 males and only one female. Most participants in the 20–40 age group spent at least one night in the farm and in the forest whereas fewer than 35% of participants from under-20 and over-40 age groups spent a night in such places. The negative binomial regression provided strong evidence that males in this cohort were more likely to spend nights in farms and in forests compared to females, and that young adults were more likely to spend nights in the forest compared to the under-20 age group , after controlling for the remaining variables . Participants may spend consecutive nights in the farms or the forests without going back home. The number of consecutive nights spent in the farms or the forests is the subset of the multiday trips mentioned in the previous section. Figure 5 quantifies this metric for different age groups and gender. Persons of all age groups and gender spent varying numbers of consecutive nights in the farms. An under-20 male spent the most consecutive nights in the farm. A female of 20–40 age-group and a male of over-40 age-group spent two episodes of 11–15 consecutive nights in the farm. In contrast, there was little demographic heterogeneity among those who spent consecutive nights in the forests. A few males of the 20–40 age group not only spent long periods of consecutive nights , but also frequently spent many short periods of consecutive nights in the forests.Many detailed human movement studies have been done, mainly in the regions of high socio-economic status. Our study presents an analysis of human movement in a remote rural area that has been under-studied with regard to human ecology . Compared to other studies where GPS loggers were used for a very short period of time, there is a relatively long duration of participation in our study. This makes it possible to examine potential seasonal variation. Our data suggest a bimodal pattern of movement away from participant homes, with one peak nearby and another one to three kilometers away from their homes . There were differences in these movement patterns by demography, with under-20s staying close to home on the majority of the days and both 20–40 and over-40 age groups tending to move farther away each day. We hypothesize that the reason for this difference is that over-20 age groups are more heavily involved in subsistence activities than the under-20 age group.

Multiday trips of less than 10 days are common among the participants. The metrics of multiday trips do not signify anything unless they are associated with the activities done during the trip which vary from visits to friends/family, getting supplies at the nearby town, farming, foraging, and other economic or subsistence activities. All age groups in this study visited farm areas and spent the night in the farms, with no statistically significant difference found between age groups. When they spent their nights in the farms, they did it consecutively and on several occasions during the study period. Farming is one of the major forms of subsistence for rural families and it must be regarded as relatively safe compared to subsistence activities in the forests that all age groups partake in it. There was no seasonal variation in the number of nights spent at the farms in these data. Different types of crops are normally rotated over the year for cultivation in this region. In contrast, going to and sleeping in the forests, which may involve foraging, logging, mining etc., is found to be the task for males of the 20–40 age group. The median number of nights slept in the forest among those who ever spent the night in the forest was 7.5. Only males of the 20–40 age group spent a higher number of nights in the forest than the median value. The same males were found to take frequent and successive overnight trips to the forests. We surmise that the males in the 20–40 age group, most likely being the breadwinners of the family, are subject to any possible subsistence activities and are regarded as the most suitable persons to venture into the forests overnight despite dangers from wildlife and harsh living conditions. No seasonal variation was found in the number of nights of sleeping in the forest. In comparison, a questionnaire based movement survey conducted in similar Thai-Myanmar border area found seasonal movement patterns. Compared to home, sleeping places in the farms and forests may be more rudimentary, leaving people more vulnerable to medically important arthropods or other environmental risks . Spending several consecutive nights in the farms and forests may increase the chances of vector-borne diseases such as malaria since major malaria vectors in the area such as Anopheles dirus, and Anopheles minimus are found in the deep forests, forest edges, plantations and even in the rice fields. Studies have found that the increased risk of malaria in forest-goers is contributed by inconsistent bed net usage, misconception that alcohol consumption or blankets provides protection against mosquito bites, non-participation in the malaria prevention activities held at the villages. Results from this study, particularly the space utilization data, would be useful in spatially explicit individual-based infectious disease model such as which models the malaria elimination in the rural South East Asian region. Human mobility is a crucial part of many disease transmission dynamics, yet it has been ignored in many infectious disease models because of constraints on data and computational capacity. Compartmental models assume homogeneous mixing of individuals in their respective compartments. While they are quick to set up, they are not suitable for the disease elimination settings. Their homogeneous nature limits the modelers from exploring the impact of multiple interventions tailored towards different risk groups such as forest-goers in malaria intervention. Individual-based models could have individual specific properties and their related movement patterns thus achieving a heterogeneous population.